Research & Educational Use Only. This protocol guide is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before beginning any research protocol.
Growth Hormone Secretagogue
Weekly Protocol Guide
Ipamorelin Protocol Guide
Ipamorelin is a selective growth hormone secretagogue that stimulates the pituitary gland to release growth hormone without significantly affecting cortisol or prolactin levels.
Protocol Overview
- Compound
- Ipamorelin (Selective GH-Releasing Peptide)
- Category
- Growth Hormone Secretagogue
- Vial Size
- 5mg (5,000mcg)
- Reconstitution
- 2mL bacteriostatic water (2.5mg/mL)
- Route
- Subcutaneous injection
- Frequency
- 2–3x daily, 5 days/week
Reconstitution Instructions
Using 2mL of bacteriostatic water results in a concentration of 2.5mg/mL. Always use sterile techniques.
Materials Needed
- 5mg Ipamorelin 5mg vial (lyophilized powder)
- 2mL bacteriostatic water (sterile, preserved with 0.9% benzyl alcohol)
- Sterile syringe and needle (18-22 gauge for drawing)
- Alcohol swabs
- Clean workspace
Step-by-Step Process
- Preparation: Allow the Ipamorelin 5mg vial and bacteriostatic water to reach room temperature. Wipe the rubber stoppers of both vials with an alcohol swab.
- Draw the Water: Using a sterile syringe, draw up exactly 2mL of bacteriostatic water. Expel any air bubbles.
- Inject into Vial: Insert the needle through the rubber stopper at a slight angle, aiming toward the glass wall. Slowly inject the water down the side of the vial to avoid foaming.
- Mix Gently: Remove the needle. Gently swirl or roll the vial between your hands. Do not shake vigorously.
- Check for Clarity: The solution should be clear once fully reconstituted. Do not use if cloudy.
Weekly Dosing Schedule
Ipamorelin is most effective when administered 2–3 times daily on an empty stomach. The bedtime dose is the most important (amplifies natural GH pulse during sleep). Avoid eating for 2+ hours before and 30 minutes after injection, as food blunts GH release.
| Protocol | Per Injection | Frequency | Daily Total | Weekly Total (5 days) |
|---|---|---|---|---|
| Standard | 200mcg (8 units) | 3x daily (AM, post-workout, before bed) | 600mcg | 3,000mcg (3mg) |
| Moderate | 200mcg (8 units) | 2x daily (AM, before bed) | 400mcg | 2,000mcg (2mg) |
| Beginner | 200mcg (8 units) | 1x daily (before bed) | 200mcg | 1,000mcg (1mg) |
Standard dose: 200–300mcg per injection, 2–3x daily • Vial Duration: ~8 days at 600mcg/day or ~25 days at 200mcg/day (5mg vial)
Quick Dosing Reference (at 2.5mg/mL)
| Units (Ticks) | Dose (mcg) | Dose (mg) |
|---|---|---|
| 4 | 100 | 0.1mg |
| 8 | 200 | 0.2mg |
| 10 | 250 | 0.25mg |
| 12 | 300 | 0.3mg |
| 20 | 500 | 0.5mg |
Administration Guidelines
- Administer subcutaneously before bed on an empty stomach (2+ hours after eating)
- Rotate injection sites between abdomen, thigh, and upper arm
- Store reconstituted peptide refrigerated at 36-46F (2-8C)
- Use reconstituted solution within 30 days
- Never freeze reconstituted peptides
- Document administration times and observations
Storage Requirements
| State | Storage Conditions |
|---|---|
| Lyophilized (powder) | Room temperature or refrigerated, protect from light |
| Reconstituted | Refrigerated 36-46F (2-8C), use within 30 days |