Best Peptides for Anti-Aging & Longevity
The peptides most studied for anti-aging and longevity include Epithalon (researched for telomerase and circadian pathways), NAD+ and SS-31 for mitochondrial function, MOTS-c for metabolic aging, and Thymalin for immune aging. Most evidence is preclinical.
Longevity peptides target the biology of aging rather than a single symptom. Epithalon is the most-discussed, studied for telomerase activity and circadian/pineal regulation. A mitochondrial group — NAD+, SS-31, MOTS-c, Humanin — is researched for cellular energy and metabolic aging. Thymalin and related thymic peptides are studied for immune aging. This is among the most preliminary categories: most data is animal or in-vitro, graded below.
⚠ Research & educational use only — not medical adviceMost-studied compounds for anti-aging & longevity
Each links to a full research protocol with reconstitution steps, research dose ranges reported in the literature, and an honest evidence grade. Ranked roughly by depth of supporting research.
Epithalon
Telomere/circadianA tetrapeptide researched for telomerase activity and pineal/circadian regulation — the most-studied longevity peptide, mostly in animal models.
View protocol →NAD+
MitochondrialResearched for cellular energy metabolism and DNA-repair pathways central to aging biology.
View protocol →SS-31
MitochondrialElamipretide — a mitochondria-targeted peptide studied for protecting cardiolipin and cellular energy production.
View protocol →MOTS-c
Metabolic agingA mitochondrial-derived peptide studied for metabolic regulation and exercise-mimetic pathways.
View protocol →Humanin
CytoprotectiveA mitochondrial-derived peptide researched for cytoprotection and metabolic-aging signaling.
View protocol →Thymalin
Immune agingA thymic peptide studied for restoring immune balance associated with aging.
View protocol →FOXO4-DRI
SenolyticA research peptide studied for selectively clearing senescent ("zombie") cells in preclinical models.
View protocol →Pinealon
NeuroprotectiveA short peptide researched for neuronal protection and circadian/aging pathways.
View protocol →Sourcing these compounds for research
Researchers studying the molecules above source cGMP-tested material from our official sponsor, LiveWell Peptides. All compounds are sold strictly for laboratory research use.
Source at LiveWell Peptides →Preferred vendor. For research use only. Not for human consumption. Not medical advice.
Plan your research
Free tools to take any compound above from vial to a documented protocol.
Frequently asked questions
No human peptide has been shown to extend human lifespan. Compounds like Epithalon show longevity signals in animal studies, but this does not translate to proven human anti-aging benefit. Treat this category as experimental.
Most research peptides discussed here are not FDA-approved for human use and are sold strictly for laboratory research purposes. A few molecules (such as certain GLP-1 receptor agonists) exist in approved prescription forms, but the research-grade material referenced on this site is not the same as a prescription product. Always consult a licensed healthcare provider before making any health decision.
It varies by compound. Some — like the GLP-1 agonists — have large human clinical trials; others (such as BPC-157 or Epithalon) rest mainly on animal and in-vitro data with limited human studies. Each protocol page on this site grades the evidence so you can see exactly what is well-supported versus preliminary.